Severe Early Life Stress Hampers Spatial Learning and Neurogenesis, but Improves Hippocampal Synaptic Plasticity and Emotional Learning under High-Stress Conditions in Adulthood

Early life stress increases the risk for developing stress-related pathologies later in life. Recent studies in rats suggest that mild early life stress, rather than being overall unfavorable, may program the hippocampus such that it is optimally adapted to a stressful context later in life. Here, w...

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Udgivet i:J Neurosci
Main Authors: Oomen, Charlotte A., Soeters, Heleen, Audureau, Nathalie, Vermunt, Lisa, van Hasselt, Felisa N., Manders, Erik M. M., Joëls, Marian, Lucassen, Paul J., Krugers, Harm
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2010
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6632559/
https://ncbi.nlm.nih.gov/pubmed/20463226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0247-10.2010
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