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Retinal Gene Distribution and Functionality Implicated in Inherited Retinal Degenerations Can Reveal Disease-Relevant Pathways for Pharmacologic Intervention

The advent of genetic therapies for inherited retinal diseases (IRDs) has spurred the need for precise diagnosis and understanding of pathways for therapeutic targeting. The majority of IRDs that are clinically diagnosed, however, lack an identifiable mutation in established disease-causing loci and...

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Detalhes bibliográficos
Publicado no:Pharmaceuticals (Basel)
Main Authors: Mustafi, Debarshi, Arbabi, Amirmohsen, Ameri, Hossein, Palczewski, Krzysztof
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6631933/
https://ncbi.nlm.nih.gov/pubmed/31108889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph12020074
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