Set-Up and Validation of a High Throughput Screening Method for Human Monoacylglycerol Lipase (MAGL) Based on a New Red Fluorescent Probe

Monoacylglycerol lipase (MAGL) is a serine hydrolase that has a key regulatory role in controlling the levels of 2-arachidonoylglycerol (2-AG), the main signaling molecule in the endocannabinoid system. Identification of selective modulators of MAGL enables both to provide new tools for investigatin...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Miceli, Matteo, Casati, Silvana, Ottria, Roberta, Di Leo, Simone, Eberini, Ivano, Palazzolo, Luca, Parravicini, Chiara, Ciuffreda, Pierangela
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6631453/
https://ncbi.nlm.nih.gov/pubmed/31208066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24122241
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