Nasal Administration and Plasma Pharmacokinetics of Parathyroid Hormone Peptide PTH 1-34 for the Treatment of Osteoporosis

Nasal delivery of large peptides such as parathyroid 1-34 (PTH 1-34) can benefit from a permeation enhancer to promote absorption across the nasal mucosa into the bloodstream. Previously, we have published an encouraging bioavailability (78%), relative to subcutaneous injection in a small animal pre...

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Bibliografiska uppgifter
I publikationen:Pharmaceutics
Huvudupphovsmän: Pearson, Richard G., Masud, Tahir, Blackshaw, Elaine, Naylor, Andrew, Hinchcliffe, Michael, Jeffery, Kirk, Jordan, Faron, Shabir-Ahmed, Anjumn, King, Gareth, Lewis, Andrew L., Illum, Lisbeth, Perkins, Alan C.
Materialtyp: Artigo
Språk:Inglês
Publicerad: MDPI 2019
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6631119/
https://ncbi.nlm.nih.gov/pubmed/31181662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics11060265
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