Mce3R Stress-Resistance Pathway Is Vulnerable to Small-Molecule Targeting That Improves Tuberculosis Drug Activities

[Image: see text] One-third of the world’s population carries Mycobacterium tuberculosis (Mtb), the infectious agent that causes tuberculosis (TB), and every 17 s someone dies of TB. After infection, Mtb can live dormant for decades in a granuloma structure arising from the host immune response, and...

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Dettagli Bibliografici
Pubblicato in:ACS Infect Dis
Autori principali: Yang, Xinxin, Yuan, Tianao, Ma, Rui, Chacko, Kieran I., Smith, Melissa, Deikus, Gintaras, Sebra, Robert, Kasarskis, Andrew, van Bakel, Harm, Franzblau, Scott G., Sampson, Nicole S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Chemical Society 2019
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6630528/
https://ncbi.nlm.nih.gov/pubmed/31012313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.9b00099
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