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Anomeric Spironucleosides of β-d-Glucopyranosyl Uracil as Potential Inhibitors of Glycogen Phosphorylase

In the case of type 2 diabetes, inhibitors of glycogen phosphorylase (GP) may prevent unwanted glycogenolysis under high glucose conditions and thus aim at the reduction of excessive glucose production by the liver. Anomeric spironucleosides, such as hydantocidin, present a rich synthetic chemistry...

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Bibliografiske detaljer
Udgivet i:Molecules
Main Authors: Stathi, Aggeliki, Mamais, Michael, Chrysina, Evangelia D., Gimisis, Thanasis
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6630470/
https://ncbi.nlm.nih.gov/pubmed/31242546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24122327
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