Polynuclear ruthenium organometallic compounds induce DNA damage in human cells identified by the nucleotide excision repair factor XPC

Ruthenium organometallic compounds represent an attractive avenue in developing alternatives to platinum-based chemotherapeutic agents. While evidence has been presented indicating ruthenium-based compounds interact with isolated DNA in vitro, it is unclear what effect these compounds exert in cells...

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Vydáno v:Biosci Rep
Hlavní autoři: Fast, Olivia G., Gentry, Brittany, Strouth, Liah, Niece, Madison B., Beckford, Floyd A., Shell, Steven M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Portland Press Ltd. 2019
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6629949/
https://ncbi.nlm.nih.gov/pubmed/31227614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20190378
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