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A liquid-like spindle domain promotes acentrosomal spindle assembly in mammalian oocytes
Mammalian oocytes segregate chromosomes with a microtubule spindle that lacks centrosomes. How acentrosomal spindles are organized and function is largely unclear. Here, we identify a conserved subcellular structure in mammalian oocytes that forms by phase separation. This structure, which we term t...
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| Publicado no: | Science |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6629549/ https://ncbi.nlm.nih.gov/pubmed/31249032 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aat9557 |
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