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Sonic hedgehog signaling in astrocytes mediates cell type-specific synaptic organization

Astrocytes have emerged as integral partners with neurons in regulating synapse formation and function, but the mechanisms that mediate these interactions are not well understood. Here, we show that Sonic hedgehog (Shh) signaling in mature astrocytes is required for establishing structural organizat...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Hill, Steven A, Blaeser, Andrew S, Coley, Austin A, Xie, Yajun, Shepard, Katherine A, Harwell, Corey C, Gao, Wen-Jun, Garcia, A Denise R
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6629371/
https://ncbi.nlm.nih.gov/pubmed/31194676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.45545
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