Angiocrine signals regulate quiescence and therapy resistance in bone metastasis

Bone provides supportive microenvironments for hematopoietic stem cells (HSCs) and mesenchymal stem cells (MSCs) and is a frequent site of metastasis. While incidences of bone metastases increase with age, the properties of the bone marrow microenvironment that regulate dormancy and reactivation of...

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Pubblicato in:JCI Insight
Autori principali: Singh, Amit, Veeriah, Vimal, Xi, Pengjun, Labella, Rossella, Chen, Junyu, Romeo, Sara G., Ramasamy, Saravana K., Kusumbe, Anjali P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2019
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6629249/
https://ncbi.nlm.nih.gov/pubmed/31292293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.125679
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