The hepatic WASH complex is required for efficient plasma LDL and HDL cholesterol clearance

The evolutionary conserved Wiskott-Aldrich syndrome protein and SCAR homolog (WASH) complex is one of the crucial multiprotein complexes that facilitates endosomal recycling of transmembrane proteins. Defects in WASH components have been associated with inherited developmental and neurological disor...

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Udgivet i:JCI Insight
Main Authors: Wijers, Melinde, Zanoni, Paolo, Liv, Nalan, Vos, Dyonne Y., Jäckstein, Michelle Y., Smit, Marieke, Wilbrink, Sanne, Wolters, Justina C., van der Veen, Ydwine T., Huijkman, Nicolette, Dekker, Daphne, Kloosterhuis, Niels, van Dijk, Theo H., Billadeau, Daniel D., Kuipers, Folkert, Klumperman, Judith, von Eckardstein, Arnold, Kuivenhoven, Jan Albert, van de Sluis, Bart
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6629119/
https://ncbi.nlm.nih.gov/pubmed/31167970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.126462
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