Computational design of improved standardized chemotherapy protocols for grade II oligodendrogliomas

Here we put forward a mathematical model describing the response of low-grade (WHO grade II) oligodendrogliomas (LGO) to temozolomide (TMZ). The model describes the longitudinal volumetric dynamics of tumor response to TMZ of a cohort of 11 LGO patients treated with TMZ. After finding patient-specif...

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Publicat a:PLoS Comput Biol
Autors principals: Pérez-García, Víctor M., Ayala-Hernández, Luis E., Belmonte-Beitia, Juan, Schucht, Philippe, Murek, Michael, Raabe, Andreas, Sepúlveda, Juan
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2019
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6629055/
https://ncbi.nlm.nih.gov/pubmed/31306418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006778
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