Mitofusin 2 plays a role in oocyte and follicle development, and is required to maintain ovarian follicular reserve during reproductive aging

Mitochondria change their shape through fusion and fission in order to adapt to their metabolic milieu. Mitofusin-2 (MFN2) is a key regulatory protein in this process, mediating mitochondrial fusion and interaction with endoplasmic reticulum. Targeted deletion of Mfn2 in oocytes resulted in mitochon...

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Bibliographische Detailangaben
Veröffentlicht in:Aging (Albany NY)
Hauptverfasser: Zhang, Man, Bener, Muhammed Burak, Jiang, Zongliang, Wang, Tianren, Esencan, Ecem, Scott, Richard, Horvath, Tamas, Seli, Emre
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals 2019
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6628992/
https://ncbi.nlm.nih.gov/pubmed/31204316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.102024
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