Long-time qingyan formula extract treatment exerts estrogenic activities on reproductive tissues without side effects in ovariectomized rats and via active ER to ERE-independent gene regulation

The reproductive tissues are negatively influenced by estrogens in hormone therapy. Qingyan formula ethanol extract (QYFE)’s estrogenic effects and safety on reproductive tissues after long-term administration and its mechanism via estrogen receptor (ER) pathway haven’t been studied. Here, we charac...

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Bibliographic Details
Published in:Aging (Albany NY)
Main Authors: Zheng, Hong-Xia, Zhao, Yuan, Xu, Ying, Zhang, Zi-Jia, Zhu, Jing-jing, Fan, Yuan-Fang, Lin, Na
Format: Artigo
Language:Inglês
Published: Impact Journals 2019
Subjects:
Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6628985/
https://ncbi.nlm.nih.gov/pubmed/31219800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.102035
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