Resistin-like molecule α provides vitamin A-dependent antimicrobial protection in the skin

Vitamin A deficiency increases susceptibility to skin infection. However, the mechanisms by which vitamin A regulates skin immunity remain unclear. Here, we show that resistin-like molecule α (RELMα), a small secreted cysteine-rich protein, is expressed by epidermal keratinocytes and sebocytes and s...

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Pubblicato in:Cell Host Microbe
Autori principali: Harris, Tamia A., Gattu, Sureka, Propheter, Daniel C., Kuang, Zheng, Bel, Shai, Ruhn, Kelly A., Chara, Andrew L., Edwards, Marshall, Zhang, Chenlu, Jo, Jay-Hyun, Raj, Prithvi, Zouboulis, Christos C., Kong, Heidi H., Segre, Julia A., Hooper, Lora V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6628910/
https://ncbi.nlm.nih.gov/pubmed/31101494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2019.04.004
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