UPLC-Q-TOF-MS profiling of the hippocampus reveals metabolite biomarkers for the impact of Dl-3-n-butylphthalide on the lipopolysaccharide-induced rat model of depression

PURPOSE: An increasing body of evidence reveals that inflammation is involved in the pathological mechanisms of depression. Our previous basic research confirmed that Dl-3-n-butylphthalide (NBP) possess anti-inflammatory properties. However, studies investigating metabolite biomarkers for the involv...

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Bibliographic Details
Published in:Neuropsychiatr Dis Treat
Main Authors: Geng, Chunmei, Guo, Yujin, Qiao, Yi, Zhang, Jun, Chen, Dan, Han, Wenxiu, Yang, Mengqi, Jiang, Pei
Format: Artigo
Language:Inglês
Published: Dove 2019
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6628600/
https://ncbi.nlm.nih.gov/pubmed/31371967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/NDT.S203870
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