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Cigarette Smoke Induces the Risk of Metabolic Bone Diseases: Transforming Growth Factor Beta Signaling Impairment via Dysfunctional Primary Cilia Affects Migration, Proliferation, and Differentiation of Human Mesenchymal Stem Cells

It is well established that smoking has detrimental effects on bone integrity and is a preventable risk factor for metabolic bone disorders. Following orthopedic surgeries, smokers frequently show delayed fracture healing associated with many complications, which results in prolonged hospital stays....

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Aspera-Werz, Romina H., Chen, Tao, Ehnert, Sabrina, Zhu, Sheng, Fröhlich, Theresa, Nussler, Andreas K.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6628373/
https://ncbi.nlm.nih.gov/pubmed/31207955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20122915
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