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A Benchmark Study of Loop Modeling Methods Applied to G Protein-Coupled Receptors

G protein-coupled receptors (GPCR) are important drug discovery targets. Despite progress, many GPCR structures have not yet been solved. For these targets, comparative modeling is used in virtual ligand screening to prioritize experimental efforts. However, the structure of extracellular loop 2 (EC...

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Detalhes bibliográficos
Publicado no:J Comput Aided Mol Des
Main Authors: Wink, Lee H., Baker, Daniel L., Cole, Judith A., Parrill-Baker, Abby L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6628340/
https://ncbi.nlm.nih.gov/pubmed/31123958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10822-019-00196-x
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