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Ligand-Based Stability Changes in Duplex DNA Measured with a Microscale Electrochemical Platform

Development of technologies for rapid screening of DNA secondary structure thermal stability and the effects on stability for binding of small molecule drugs is important to the drug discovery process. In this report, we describe the capabilities of an electrochemical, microdevice-based approach for...

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Podrobná bibliografie
Vydáno v:Biosensors (Basel)
Hlavní autoři: Robinson, Sarah M., Shen, Zuliang, Askim, Jon R., Montgomery, Christopher B., Sintim, Herman O., Semancik, Steve
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6628196/
https://ncbi.nlm.nih.gov/pubmed/31013753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/bios9020054
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