Comprehensive Profiling of Primary and Metastatic ccRCC Reveals a High Homology of the Metastases to a Subregion of the Primary Tumour

While intratumour genetic heterogeneity of primary clear cell renal cell carcinoma (ccRCC) is well characterized, the genomic profiles of metastatic ccRCCs are seldom studied. We profiled the genomes and transcriptomes of a primary tumour and matched metastases to better understand the evolutionary...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Ferronika, Paranita, Hof, Joost, Kats-Ugurlu, Gursah, Sijmons, Rolf H., Terpstra, Martijn M., de Lange, Kim, Leliveld-Kors, Annemarie, Westers, Helga, Kok, Klaas
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6628027/
https://ncbi.nlm.nih.gov/pubmed/31212796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11060812
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