DNAM-1 and the TIGIT/PVRIG/TACTILE Axis: Novel Immune Checkpoints for Natural Killer Cell-Based Cancer Immunotherapy

Natural killer (NK) cells are lymphocytes of the innate immune response characterized by their role in the destruction of tumor cells. Activation of NK cells depend on a fine balance between activating and inhibitory signals mediated by different receptors. In recent years, a family of paired recept...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Sanchez-Correa, Beatriz, Valhondo, Isabel, Hassouneh, Fakhri, Lopez-Sejas, Nelson, Pera, Alejandra, Bergua, Juan M., Arcos, Maria Jose, Bañas, Helena, Casas-Avilés, Ignacio, Durán, Esther, Alonso, Corona, Solana, Rafael, Tarazona, Raquel
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6628015/
https://ncbi.nlm.nih.gov/pubmed/31234588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11060877
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