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Serine Protease from Nereis virens Inhibits H1299 Lung Cancer Cell Proliferation via the PI3K/AKT/mTOR Pathway

This study explores the in vitro anti-proliferative mechanism between Nereis Active Protease (NAP) and human lung cancer H1299 cells. Colony formation and migration of cells were significantly lowered, following NAP treatment. Flow cytometry results suggested that NAP-induced growth inhibition of H1...

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Detalhes bibliográficos
Publicado no:Mar Drugs
Main Authors: Chen, Yanan, Tang, Yunping, Tang, Yanhua, Yang, Zuisu, Ding, Guofang
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6627947/
https://ncbi.nlm.nih.gov/pubmed/31226829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md17060366
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