FBXW5 Promotes Tumorigenesis and Metastasis in Gastric Cancer via Activation of the FAK-Src Signaling Pathway

F-box/WD repeat-containing protein 5 (FBXW5) is a member of the FBXW subclass of F-box proteins. Despite its known function as a component of the Skp1-Cullin-F-box (SCF) ubiquitin ligase complex, the role of FBXW5 in gastric cancer tumorigenesis and metastasis has not been investigated. The present...

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Veröffentlicht in:Cancers (Basel)
Hauptverfasser: Yeo, Mei Shi, Vijay Subhash, Vinod, Suda, Kazuto, Emrah Balcıoğlu, Hayri, Zhou, Siqin, Thuya, Win Lwin, Loh, Xin Yi, Jammula, Sriganesh, Peethala, Praveen C., Tan, Shi Hui, Xie, Chen, Wong, Foong Ying, Ladoux, Benoit, Ito, Yoshiaki, Yang, Henry, Goh, Boon Cher, Wang, Lingzhi, Yong, Wei Peng
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6627937/
https://ncbi.nlm.nih.gov/pubmed/31213005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11060836
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