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Rational Design of Alginate Lyase from Microbulbifer sp. Q7 to Improve Thermal Stability

Alginate lyase degrades alginate by the β-elimination mechanism to produce oligosaccharides with special bioactivities. The low thermal stability of alginate lyase limits its industrial application. In this study, introducing the disulfide bonds while using the rational design methodology enhanced t...

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Publicado en:Mar Drugs
Main Authors: Yang, Min, Yang, Su-Xiao, Liu, Zhe-Min, Li, Nan-Nan, Li, Li, Mou, Hai-Jin
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6627800/
https://ncbi.nlm.nih.gov/pubmed/31242622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md17060378
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