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PARP Inhibitors in Ovarian Cancer: The Route to “Ithaca”
Poly (ADP-ribose) polymerase (PARP) inhibitors are a novel class of therapeutic agents that target tumors with deficiencies in the homologous recombination DNA repair pathway. Genomic instability characterizes high-grade serous ovarian cancer (HGSOC), with one half of all tumors displaying defects i...
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| Publicado no: | Diagnostics (Basel) |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6627688/ https://ncbi.nlm.nih.gov/pubmed/31109041 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/diagnostics9020055 |
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