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Phase I Dose Escalation Study with Expansion Cohort of the Addition of Nab-Paclitaxel to Capecitabine and Oxaliplatin (CapOx) as First-Line Treatment of Metastatic Esophagogastric Adenocarcinoma (ACTION Study)

First-line triplet chemotherapy including a taxane may prolong survival in patients with metastatic esophagogastric cancer. The added toxicity of the taxane might be minimized by using nab-paclitaxel. The aim of this phase I study was to determine the feasibility of combining nab-paclitaxel with the...

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Bibliografski detalji
Izdano u:Cancers (Basel)
Glavni autori: Schokker, Sandor, van der Woude, Stephanie O., van Kleef, Jessy Joy, van Zoen, Daan J., van Oijen, Martijn G. H., Mearadji, Banafsche, Beenen, Ludo F. M., Stroes, Charlotte I., Waasdorp, Cynthia, Jibodh, R. Aarti, Creemers, Aafke, Meijer, Sybren L., Hooijer, Gerrit K. J., Punt, Cornelis J. A., Bijlsma, Maarten F., van Laarhoven, Hanneke W. M.
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6627561/
https://ncbi.nlm.nih.gov/pubmed/31207904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11060827
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