Modeling of LMNA-Related Dilated Cardiomyopathy Using Human Induced Pluripotent Stem Cells

Dilated cardiomyopathy (DCM) is one of the leading causes of heart failure and heart transplantation. A portion of familial DCM is due to mutations in the LMNA gene encoding the nuclear lamina proteins lamin A and C and without adequate treatment these patients have a poor prognosis. To get better i...

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Bibliografiska uppgifter
I publikationen:Cells
Huvudupphovsmän: Shah, Disheet, Virtanen, Laura, Prajapati, Chandra, Kiamehr, Mostafa, Gullmets, Josef, West, Gun, Kreutzer, Joose, Pekkanen-Mattila, Mari, Heliö, Tiina, Kallio, Pasi, Taimen, Pekka, Aalto-Setälä, Katriina
Materialtyp: Artigo
Språk:Inglês
Publicerad: MDPI 2019
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6627421/
https://ncbi.nlm.nih.gov/pubmed/31208058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8060594
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