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Identification of Small Molecule Inhibitors of Staphylococcus aureus RnpA

Staphylococcus aureus RnpA is thought to be a unique dual functional antimicrobial target that is required for two essential cellular processes, precursor tRNA processing and messenger RNA degradation. Herein, we used a previously described whole cell-based mupirocin synergy assay to screen members...

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Bibliographic Details
Published in:Antibiotics (Basel)
Main Authors: Colquhoun, Jennifer M., Ha, Lisha, Beckley, Andrew, Meyers, Brinkley, Flaherty, Daniel P., Dunman, Paul M.
Format: Artigo
Language:Inglês
Published: MDPI 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6627331/
https://ncbi.nlm.nih.gov/pubmed/31035380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antibiotics8020048
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