Jatrorrhizine inhibits colorectal carcinoma proliferation and metastasis through Wnt/β-catenin signaling pathway and epithelial–mesenchymal transition

PURPOSE: Jatrorrhizine (JAT) is a natural protoberberine alkaloid, possesses detoxification, bactericidal and hypoglycemic activities. However, its anti-cancer mechanism is not clear. This study aimed to investigate the mechanism of JAT through which inhibits colorectal cancer in HCT-116 and HT-29 c...

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Dades bibliogràfiques
Publicat a:Drug Des Devel Ther
Autors principals: Wang, Pan, Gao, Xiao-Yan, Yang, Si-Qian, Sun, Zhi-Xin, Dian, Lu-Lu, Qasim, Muhammad, Phyo, Aung Thu, Liang, Zong-Suo, Sun, Yan-Fang
Format: Artigo
Idioma:Inglês
Publicat: Dove 2019
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6627180/
https://ncbi.nlm.nih.gov/pubmed/31371920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S207315
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