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From Powerhouse to Perpetrator—Mitochondria in Health and Disease

In this review we discuss the interaction between metabolic stress, mitochondrial dysfunction, and genomic instability. Unrepaired DNA damage in the nucleus resulting from excess accumulation of DNA damages and stalled replication can initiate cellular signaling responses that negatively affect meta...

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Detalhes bibliográficos
Publicado no:Biology (Basel)
Main Authors: Fakouri, Nima B., Hansen, Thomas Lau, Desler, Claus, Anugula, Sharath, Rasmussen, Lene Juel
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6627154/
https://ncbi.nlm.nih.gov/pubmed/31083572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biology8020035
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