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Cooperativity between stromal cytokines drives the invasive migration of human breast cancer cells

The cross-talk between cancer cells and the stromal microenvironment plays a key role in regulating cancer invasion. Here, we employed an ex vivo invasion model system for exploring the regulation of breast cancer cells infiltration into a variety of stromal fibroblast monolayers. Our results reveal...

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Detalles Bibliográficos
Publicado en:Philos Trans R Soc Lond B Biol Sci
Autores principales: Elisha, Yair, Sagi, Yael, Klein, Georg, Straussman, Ravid, Geiger, Benjamin
Formato: Artigo
Lenguaje:Inglês
Publicado: The Royal Society 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6627018/
https://ncbi.nlm.nih.gov/pubmed/31431170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2018.0231
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