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Screening miRNAs associated with resistance gemcitabine from exosomes in A549 lung cancer cells

PURPOSE: To establish a gemcitabine-resistant lung adenocarcinoma cell line, A549/G+, and to screen the differences of miRNA expression in exosomes from A549 and A549/G+ cells. METHODS: A549 cells were exposed in gemcitabine until they were resistant to gemcitabine, and extracted exosomes from A549...

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Detalhes bibliográficos
Publicado no:Cancer Manag Res
Main Authors: Liang, Ai-Ling, Du, Shen-Lin, Zhang, Bin, Zhang, Jing, Ma, Xuan, Wu, Cui-Yun, Liu, Yong-Jun
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6626902/
https://ncbi.nlm.nih.gov/pubmed/31372037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S209149
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