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Response to combined ipilimumab and nivolumab after development of a nephrotic syndrome related to PD-1 monotherapy

BACKGROUND: High response rates of metastatic melanoma have been reported upon immune checkpoint inhibition by PD-1 blockade alone or in combination with CTLA-4 inhibitors. However, the majority of patients with a primary resistance to anti-PD-1 monotherapy is also refractory to a subsequent combine...

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Detalhes bibliográficos
Publicado no:J Immunother Cancer
Main Authors: Glutsch, Valerie, Grän, Franziska, Weber, Judith, Gesierich, Anja, Goebeler, Matthias, Schilling, Bastian
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6626404/
https://ncbi.nlm.nih.gov/pubmed/31300044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40425-019-0655-4
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