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Molecular basis of egg coat cross-linking sheds light on ZP1-associated female infertility
Mammalian fertilisation begins when sperm interacts with the egg zona pellucida (ZP), whose ZP1 subunit is important for fertility by covalently cross-linking ZP filaments into a three-dimensional matrix. Like ZP4, a structurally-related component absent in the mouse, ZP1 is predicted to contain an...
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| Udgivet i: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6626044/ https://ncbi.nlm.nih.gov/pubmed/31300655 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10931-5 |
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