Increased LIGHT leading to sFlt-1 elevation underlies the pathogenic link between hydatidiform mole and preeclampsia

Hydatidiform moles are known to pose an extremely high risk of severe early-onset preeclampsia if left untreated. TNF superfamily cytokine, LIGHT has recently been reported to contribute to pathophysiology of preeclampsia. The present study aimed to investigate the involvement of LIGHT in hydatidifo...

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Pubblicato in:Sci Rep
Autori principali: Iriyama, Takayuki, Wang, Guan, Yoshikawa, Midori, Mimura, Nobuko, Matsui, Haruka, Sayama, Seisuke, Kumasawa, Keiichi, Nagamatsu, Takeshi, Koga, Kaori, Kotani, Tomomi, Niimi, Kaoru, Yamamoto, Eiko, Kellems, Rodney E., Xia, Yang, Osuga, Yutaka, Fujii, Tomoyuki
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6625991/
https://ncbi.nlm.nih.gov/pubmed/31300808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-46660-4
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