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A coupled Reaction-Diffusion-Strain model predicts cranial vault formation in development and disease

How cells utilize instructions provided by genes and integrate mechanical forces generated by tissue growth to produce morphology is a fundamental question of biology. Dermal bones of the vertebrate cranial vault are formed through the direct differentiation of mesenchymal cells on the neural surfac...

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Bibliographic Details
Published in:Biomech Model Mechanobiol
Main Authors: Lee, Chanyoung, Richtsmeier, Joan T., Kraft, Reuben H.
Format: Artigo
Language:Inglês
Published: 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6625897/
https://ncbi.nlm.nih.gov/pubmed/31006064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10237-019-01139-z
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