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DART-ID increases single-cell proteome coverage

Analysis by liquid chromatography and tandem mass spectrometry (LC-MS/MS) can identify and quantify thousands of proteins in microgram-level samples, such as those comprised of thousands of cells. This process, however, remains challenging for smaller samples, such as the proteomes of single mammali...

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Dettagli Bibliografici
Pubblicato in:PLoS Comput Biol
Autori principali: Chen, Albert Tian, Franks, Alexander, Slavov, Nikolai
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6625733/
https://ncbi.nlm.nih.gov/pubmed/31260443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1007082
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