CBP-1 Acts in GABAergic Neurons to Double Life Span in Axenically Cultured Caenorhabditis elegans

When cultured in axenic medium, Caenorhabditis elegans shows the largest life-span extension compared with other dietary restriction regimens. However, the underlying molecular mechanism still remains elusive. The gene cbp-1, encoding the worm ortholog of p300/CBP (CREB-binding protein), is one of t...

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Bibliografske podrobnosti
izdano v:J Gerontol A Biol Sci Med Sci
Main Authors: Cai, Huaihan, Dhondt, Ineke, Vandemeulebroucke, Lieselot, Vlaeminck, Caroline, Rasulova, Madina, Braeckman, Bart P
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2019
Teme:
The Journal of Gerontology: Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6625597/
https://ncbi.nlm.nih.gov/pubmed/29099917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glx206
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