Significant reduction of ischemia‐reperfusion cell death in mouse myocardial infarcts using the immediate‐acting PrC‐210 ROS‐scavenger

Managing myocardial infarction (MI) to reduce cardiac cell death relies primarily on timely reperfusion of the affected coronary site, but reperfusion itself induces cell death through a toxic, ROS‐mediated process. In this study, we determined whether the PrC‐210 aminothiol ROS‐scavenger could prev...

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Detalhes bibliográficos
Publicado no:Pharmacol Res Perspect
Main Authors: Hacker, Timothy A., Diarra, Gaoussou, Fahl, Bryan L., Back, Susan, Kaufmann, Erin, Fahl, William E.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6625532/
https://ncbi.nlm.nih.gov/pubmed/31338199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.500
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