High glucose microenvironment accelerates tumor growth via SREBP1-autophagy axis in pancreatic cancer

BACKGROUND: Diabetes is recognized to be a risk factor of pancreatic cancer, but the mechanism has not been fully elucidated. Sterol regulatory element binding protein 1 (SREBP1) is an important transcription factor involved in both lipid metabolism and tumor progression. However, the relationship b...

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Bibliografski detalji
Izdano u:J Exp Clin Cancer Res
Glavni autori: Zhou, Cancan, Qian, Weikun, Li, Jie, Ma, Jiguang, Chen, Xin, Jiang, Zhengdong, Cheng, Liang, Duan, Wanxing, Wang, Zheng, Wu, Zheng, Ma, Qingyong, Li, Xuqi
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2019
Teme:
Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6625066/
https://ncbi.nlm.nih.gov/pubmed/31296258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1288-7
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