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Contrasting Gene Expression Profiles of Monocytes and Lymphocytes From Peste-Des-Petits-Ruminants Virus Infected Goats

In this study, transcriptome analysis of PPRV infected PBMC subsets—T helper cells, T cytotoxic cells, monocytes, and B lymphocytes was done to delineate their role in host response. PPRV was found to infect lymphocytes and not monocytes. The established receptor for PPRV—SLAM was found downregulate...

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Veröffentlicht in:Front Immunol
Hauptverfasser: Wani, Sajad Ahmad, Sahu, Amit Ranjan, Khan, Raja Ishaq Nabi, Pandey, Aruna, Saxena, Shikha, Hosamani, Neelima, Malla, Waseem Akram, Chaudhary, Dheeraj, Kanchan, Sonam, Sah, Vaishali, Rajak, Kaushal Kishor, Muthuchelvan, D., Mishra, Bina, Tiwari, Ashok Kumar, Sahoo, Aditya P., Sajjanar, Basavaraj, Singh, Yash Pal, Gandham, Ravi Kumar, Mishra, Bishnu Prasad, Singh, Raj Kumar
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6624447/
https://ncbi.nlm.nih.gov/pubmed/31333643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01463
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