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Exposure‐response modeling of tocilizumab in rheumatoid arthritis using continuous composite measures and their individual components
AIMS: Tocilizumab has a direct effect on inflammatory markers. Therefore, composite measures for disease activity assessment in rheumatoid arthritis (RA) using these inflammatory markers may not be suitable for tocilizumab treatment. We used a modelling approach to describe the tocilizumab exposure‐...
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| Publicado no: | Br J Clin Pharmacol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6624405/ https://ncbi.nlm.nih.gov/pubmed/30958574 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13954 |
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