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Hepatic exposure of metformin in patients with non‐alcoholic fatty liver disease

AIMS: Metformin is first‐line treatment of type 2 diabetes mellitus and reduces cardiovascular events in patients with insulin resistance and type 2 diabetes. Target tissue for metformin action is thought to be the liver, where metformin distribution depends on facilitated transport by polyspecific...

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Detaylı Bibliyografya
Yayımlandı:Br J Clin Pharmacol
Asıl Yazarlar: Sundelin, Elias Immanuel Ordell, Gormsen, Lars Christian, Heebøll, Sara, Vendelbo, Mikkel Holm, Jakobsen, Steen, Munk, Ole Lajord, Feddersen, Søren, Brøsen, Kim, Hamilton‐Dutoit, Stephen Jacques, Pedersen, Steen Bønløkke, Grønbæk, Henning, Jessen, Niels
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2019
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6624391/
https://ncbi.nlm.nih.gov/pubmed/30973968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13962
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