Icariin-mediated activation of autophagy confers protective effect on rotenone induced neurotoxicity in vivo and in vitro

Rotenone (ROT) is an environmental neurotoxin which has been demonstrated to cause characteristic loss of dopamine (DA) neurons in Parkinson’s disease (PD). Icariin (ICA) is a flavonoid glucoside isolated from Herba Epimedii that has been shown to display neuroprotective functions. The present study...

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Bibliographic Details
Published in:Toxicol Rep
Main Authors: Zeng, Ru, Zhou, Qian, Zhang, Wei, Fu, Xiaolong, Wu, Qin, Lu, Yuanfu, Shi, Jingshan, Zhou, Shaoyu
Format: Artigo
Language:Inglês
Published: Elsevier 2019
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6624214/
https://ncbi.nlm.nih.gov/pubmed/31334034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxrep.2019.06.014
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