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Icariin-mediated activation of autophagy confers protective effect on rotenone induced neurotoxicity in vivo and in vitro

Rotenone (ROT) is an environmental neurotoxin which has been demonstrated to cause characteristic loss of dopamine (DA) neurons in Parkinson’s disease (PD). Icariin (ICA) is a flavonoid glucoside isolated from Herba Epimedii that has been shown to display neuroprotective functions. The present study...

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Detalhes bibliográficos
Publicado no:Toxicol Rep
Main Authors: Zeng, Ru, Zhou, Qian, Zhang, Wei, Fu, Xiaolong, Wu, Qin, Lu, Yuanfu, Shi, Jingshan, Zhou, Shaoyu
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6624214/
https://ncbi.nlm.nih.gov/pubmed/31334034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxrep.2019.06.014
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