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Icariin-mediated activation of autophagy confers protective effect on rotenone induced neurotoxicity in vivo and in vitro

Rotenone (ROT) is an environmental neurotoxin which has been demonstrated to cause characteristic loss of dopamine (DA) neurons in Parkinson’s disease (PD). Icariin (ICA) is a flavonoid glucoside isolated from Herba Epimedii that has been shown to display neuroprotective functions. The present study...

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Dettagli Bibliografici
Pubblicato in:Toxicol Rep
Autori principali: Zeng, Ru, Zhou, Qian, Zhang, Wei, Fu, Xiaolong, Wu, Qin, Lu, Yuanfu, Shi, Jingshan, Zhou, Shaoyu
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6624214/
https://ncbi.nlm.nih.gov/pubmed/31334034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxrep.2019.06.014
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