A new severe acute necrotizing pancreatitis model induced by l-ornithine in rats

OBJECTIVE: Intraperitoneal administration of large doses of l-arginine is known to induce severe acute pancreatitis in rats. We therefore set out to determine whether metabolites of l-arginine (l-ornithine, l-citrulline, and nitric oxide) cause pancreatitis. DESIGN: The authors conducted an in vivo...

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Publicado en:Crit Care Med
Main Authors: Rakonczay, Zoltán, Hegyi, Péter, Dósa, Sándor, Iványi, Béla, Jármay, Katalin, Biczó, György, Hracskó, Zsuzsanna, Varga, Ilona S., Karg, Eszter, Kaszaki, József, Varró, András, Lonovics, János, Boros, Imre, Gukovsky, Ilya, Gukovskaya, Anna S., Pandol, Stephen J., Takács, Tamás
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6624069/
https://ncbi.nlm.nih.gov/pubmed/18594222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CCM.0b013e31817d7f5c
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