The Chemokine CCL2 Increases Na(v)1.8 Sodium Channel Activity in Primary Sensory Neurons through a Gβγ-Dependent Mechanism

Changes in function of voltage-gated sodium channels in nociceptive primary sensory neurons participate in the development of peripheral hyperexcitability that occurs in neuropathic and inflammatory chronic pain conditions. Among them, the tetrodotoxin-resistant (TTX-R) sodium channel Na(v)1.8, prim...

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Publicado no:J Neurosci
Main Authors: Belkouch, Mounir, Dansereau, Marc-André, Réaux-Le Goazigo, Annabelle, Van Steenwinckel, Juliette, Beaudet, Nicolas, Chraibi, Ahmed, Melik-Parsadaniantz, Stéphane, Sarret, Philippe
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2011
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6623900/
https://ncbi.nlm.nih.gov/pubmed/22171040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3386-11.2011
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