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Thalamocortical Pathfinding Defects Precede Degeneration of the Reticular Thalamic Nucleus in Polysialic Acid-Deficient Mice

The modification of the neural cell adhesion molecule (NCAM) with polysialic acid (polySia) is tightly linked to neural development. Genetic ablation of the polySia-synthesizing enzymes ST8SiaII and ST8SiaIV generates polySia-negative but NCAM-positive (II(−/−)IV(−/−)) mice characterized by severe d...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Schiff, Miriam, Röckle, Iris, Burkhardt, Hannelore, Weinhold, Birgit, Hildebrandt, Herbert
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6623622/
https://ncbi.nlm.nih.gov/pubmed/21273415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5609-10.2011
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