Targeting Mannitol Metabolism as an Alternative Antimicrobial Strategy Based on the Structure-Function Study of Mannitol-1-Phosphate Dehydrogenase in Staphylococcus aureus

Mannitol-1-phosphate dehydrogenase (M1PDH) is a key enzyme in Staphylococcus aureus mannitol metabolism, but its roles in pathophysiological settings have not been established. We performed comprehensive structure-function analysis of M1PDH from S. aureus USA300, a strain of community-associated met...

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Vydáno v:mBio
Hlavní autoři: Nguyen, Thanh, Kim, Truc, Ta, Hai Minh, Yeo, Won Sik, Choi, Jongkeun, Mizar, Pushpak, Lee, Seung Seo, Bae, Taeok, Chaurasia, Akhilesh Kumar, Kim, Kyeong Kyu
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2019
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6623548/
https://ncbi.nlm.nih.gov/pubmed/31289190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02660-18
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