Suppression of a Neocortical Potassium Channel Activity by Intracellular Amyloid-β and Its Rescue with Homer1a

It is proposed that intracellular amyloid-β (Aβ), before extracellular plaque formation, triggers cognitive deficits in Alzheimer disease (AD). Here we report how intracellular Aβ affects neuronal properties. This was done by injecting Aβ protein into rat and mouse neocortical pyramidal cells throug...

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Bibliografiska uppgifter
I publikationen:J Neurosci
Huvudupphovsmän: Yamamoto, Kenji, Ueta, Yoshifumi, Wang, Li, Yamamoto, Ryo, Inoue, Naoko, Inokuchi, Kaoru, Aiba, Atsu, Yonekura, Hideto, Kato, Nobuo
Materialtyp: Artigo
Språk:Inglês
Publicerad: Society for Neuroscience 2011
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Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6623357/
https://ncbi.nlm.nih.gov/pubmed/21813671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.6752-10.2011
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