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Wnt/β-Catenin Signaling Is an Essential and Direct Driver of Myelin Gene Expression and Myelinogenesis

Wnt/β-catenin signaling plays a major role in the development of the nervous system and contributes to neuronal plasticity. However, its role in myelination remains unclear. Here, we identify the Wnt/β-catenin pathway as an essential driver of myelin gene expression. The selective inhibition of Wnt...

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Publicat a:J Neurosci
Autors principals: Tawk, Marcel, Makoukji, Joelle, Belle, Martin, Fonte, Cosima, Trousson, Amalia, Hawkins, Thomas, Li, Huiliang, Ghandour, Said, Schumacher, Michael, Massaad, Charbel
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6622795/
https://ncbi.nlm.nih.gov/pubmed/21389228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4270-10.2011
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